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Perimenopause: Understanding This Transition and Supporting Your Body Well

Supportive strategies to help women adapt to the changes in their body during perimenopause.

Alexia Gillen of Mosaic Medicine

Dr. Alexia Gillen

EXPERT CONTRIBUTOR

Owner, Mosaic Medicine

Q: Could perimenopause be causing the changes I’m noticing in my body?

If you’ve started feeling like your body is changing in ways you don’t fully recognize, you are not alone — and you are not imagining it.

For many women, midlife brings a shift that can feel subtle at first and then suddenly hard to ignore. You may notice changes in your sleep, mood, energy, weight, focus, cycles, libido, or stress tolerance. You may feel more irritable, more tired, more inflamed, or simply less like yourself. These experiences are common, and they are often part of the hormonal transition known as perimenopause.

Middle-aged women sharing sushi and wine

Perimenopause is the phase leading up to menopause, and it can begin years before periods stop completely. During this time, hormone levels often fluctuate before they decline, which is one reason symptoms can feel unpredictable. Some women experience hot flashes and night sweats, while others notice anxiety, brain fog, poor sleep, heavier periods, joint pain, or changes in body composition. Hormonal shifts can also affect the musculoskeletal system, contributing to joint discomfort, loss of muscle mass, bone-density changes, and reduced physical resilience.Ā 

That is why this transition deserves more than a ā€œjust push through itā€ approach.

One of the most helpful mindset shifts women can make is this: your body is not failing — it is adapting. The goal is not to fight your body, but to better understand what it needs now. For many women, that starts with looking at symptoms as connected rather than isolated. Poor sleep, fatigue, mood changes, weight gain, low motivation, and increased stress sensitivity are often not random. They may reflect a larger hormonal and physiologic pattern that deserves attention.

There is good news: supportive strategies can make a real difference. Strength training is one of the most important tools in midlife because it helps preserve lean muscle, supports bone health, improves physical function, and can positively influence body composition and metabolic health when done consistently. Nutrition also matters. Prioritizing protein, fiber, blood-sugar stability, and anti-inflammatory foods can support energy, mood, metabolism, and resilience. Sleep and stress support are equally important, because poor sleep and chronic stress can intensify many common perimenopausal symptoms.

Middle-aged woman lifting small hand-held weight

For some women, hormone therapy can also be an important part of care. Menopause hormone therapy is considered the most effective treatment for bothersome hot flashes and night sweats, and it can also help with sleep disruption, vaginal dryness, painful intercourse, and some urinary symptoms.Ā 

For many healthy women, hormone therapy can offer benefits beyond symptom relief when started around the time of menopause. In addition to helping with hot flashes, night sweats, and sleep disruption, it also supports bone health, brain health and heart health. That said, hormone therapy is not a one-size-fits-all treatment. The best approach depends on your symptoms, age, medical history, your personal risk factors, and your overall health goals.Ā 

This is why it is so important for women to know that they do not have to guess their way through this transition alone. If symptoms are affecting your quality of life, it is worth talking with a knowledgeable physician about your options. A thoughtful evaluation can help clarify what is hormonal, what may be metabolic or thyroid-related, and whether lifestyle changes, hormone therapy, or other treatments may be appropriate.

Perimenopause is a real physiologic transition, but it does not have to be a silent or confusing one. With the right support, many women find that this season becomes not only more manageable, but also an opportunity to feel stronger, more informed, and more connected to their health moving forward.

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